Boys and young men of color are overrepresented in all aspects of the juvenile justice and criminal justice systems, at considerable cost to those involved, their families, and their communities. This overrepresentation is most acute for African Americans, although other communities of color are also affected. This brief reviews systemic, institutional, and community policies and practices that greatly impact the life chances of boys and young men of color. Policy and practice changes that would reduce criminal justice engagement and that would reduce the harms caused to communities of color from criminal justice engagement are identified and suggestions are made for developing more evidence of effectiveness for initiatives in this area.